KMID : 0363020080380010031
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Journal of Korean Academy of Periodontology 2008 Volume.38 No. 1 p.31 ~ p.39
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Inhibitory effects of Enterococcus faecium isolated from Korean infants on oral pathogens
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Jung Eun-Gyeong
Lee Jong-Cheol Seo Jung-Yoon Kim Seong-Yoon Kim Wan-Su Yun Woo-Hyuk Kim Yun-Sang Pi Sung-Hee Yoo Hyung-Keun Shin Hyung-Shik
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Abstract
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Purpose : The probiotic effects of lactic acid bacteria have widely been researched in diverse human pathogens, but only a few effects are reported against oral pathogens. The antimicrobial effects of the Enterococcus faecium 7413
isolated from Korean infants on the 9 pathogen including 6 oral streptococci were investigated the clinical use of the
antimicrobial peptide for oral microflora control.
Materials & Methods : E. faecium 7413 was identified by morphological, biochemical tests and 16S rDNA
sequence analysis. Inhibitory effects of culture supernatants were determined for their ability to grow on agar plate
containing pathogenic bacteria.
Results : The culture supernatant of Enterococcus faecium 7413 showed inhibitory effects on oral pathogens, namely Streptococcus pyogenes KCTC 3556, S. pneumoniae KCTC 5080, S. mutans ATCC 25175, S. anginosus ATCC 33397, S. constellatus KCTC 3268, S. intermedius ATCC 27823 and Shigella flexneri KCTC 2008. Whereas it did not affect
the multiplication of E. coli strains, KCTC 1041 and ATCC 43894.
Conclusion : The data obtained in this study could be useful for future development of effective probiotics allowing
prevention for oral pathogens. (J Korean Acad Periodontol 2008;38:31-40)
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KEYWORD
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Enterococcus faecium, infant, oral pathogens
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